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Resources (448)

Cell-based assays, Cell-based assay screening

Liu et al., Surviving cells after treatment with gemcitabine or 5-fluorouracil for the study of de novo resistance of pancreatic cancer– Cancer Letters, 2012 Jan 1;314(1):119-25

Cell-based assays, Cell-based assay screening

Lee et al., High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them. Methods, Eprint 5th April 2012

Cell-based assays, Cell-based assay screening

Heald et al., Discovery of Novel Allosteric Mitogen-Activated Protein Kinase Kinase (MEK) 1,2 Inhibitors Possessing Bidentate Ser212 Interactions. J. Med. Chem. 2012, 55, 4594−4604

Cell-based assay screening

Gerlinger et al., Genome‐wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. J. Pathol 2012 Feb 24

Compound management

Gaisford, W. (2012) The future of sample management: Part 1. Pharma July/August p43

mosquito HV genomics

Gaisford, W. (2012) Robotic liquid handling and automation in epigenetics. JALA

Hanging drop crystallization

Koide, A., J. Wojcik, et al. (2012). Teaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 Scaffold. J Mol Biol 415(2): 393-405.

Sitting drop crystallization

Brelidze, T. I. et al (2012) Structure of the carboxy-terminal region of a KCNH channel. Nature 481: 530–533

Cell-based assays, Cell-based assay screening

Gaisford, W. Evolving methods in cytology: its the era of laser scanning, imaging-based technology. MLO, Dec 2011

Lipidic Cubic Phase (in-meso), Hanging drop crystallization, Crystal screen optimization, Sitting drop crystallization

LabCrystal 11

Cell-based assays

Zhao, G et al. A Novel, Selective Inhibitor of Fibroblast Growth Factor Receptors That Shows A Potent Broad-spectrum of Anti-tumor Activity in Several Tumor Xenograft Models. MCT, Sept 2011.

Cell-based assays

Meier, T et al. Tasisulam Sodium, an Anti-tumor Agent that Inhibits Mitotic Progression and Induces Vascular Normalization. MCT, Sept 2011.

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