Positive displacement pipetting: the accurate way to handle liquids
Revolutionary, automated positive displacement pipetting
The difficulties of pipetting accurately at low volumes are well known, as are issues associated with handling viscous liquids. Our innovative technology development team have overcome these with the novel use of positive displacement dispensing from disposable tips in all of our liquid handling products.
What is positive displacement?
Positive displacement pipetting is defined by the fact that the piston, moving the liquid in and out of the tip for aspiration and dispensing, comes into direct contact with the liquid itself.
This piston based pipetting action results in highly accurate liquid handling across a very broad volume and viscosity range.
Products powered by this technology
mosquito® uses positive displacement, disposable micropipettes to handle low volumes (25 nL - 5 uL) of liquid in
dragonfly® handles much larger volumes (200 nL up to 4 mL) using disposable positive displacement tips to aspirate from reservoirs and dispense non-contact to wells within plates. It is therefore ideal for combination and bulk reagent dispensing as well as accurate handling of difficult liquids classes.
reduced set up time and training requirements
intuitive and logical operation simplifies user experience
no liquid classification requirements
accurate dispensing, irrespective of liquid type
rugged and robust performance
disposable tips, piston based pipetting and no pressure system or valves
more than just dispensing
our instruments are true pipettors able to aspirate, dispense and even mix
do more with less
direct sample aspiration ensures minimal dead volumes
accurate and repeatable dispensing
innovative automated positive displacement pipetting
mosquito: accurate low volume pipetting
Each of mosquito’s disposable micropipettes has its own individual piston, not an air gap or system liquid, offering true positive-displacement pipetting with no risk of cross-contamination. This provides accurate and repeatable nanolitre to microlitre pipetting, every time, irrespective of liquid viscosity.
dragonfly: revolutionary non-contact dispensing
Each of dragonfly’s disposable tips has its own individual piston, not an air gap or system liquid, offering true positive-displacement, non-contact dispensing with no risk of cross-contamination. This provides accurate, repeatable and highly reliable, wide dynamic range dispensing, every time, irrespective of liquid viscosity.
Our range of liquid handling instruments are invaluable where flexibility, usability and rapid generation of high quality data is essential to reducing the drug discovery cycle time. Applications range from assay development, including DoE, through HTS, hit-to-lead and lead optimisation.
The unique benefits of positive displacement technology have ensured that mosquito crystal, LCP and dragonfly crystal have become industry standard tools for crystal screening and optimisation.
Maximise data output, whilst significantly reducing sample and reagent costs within a genomics research laboratory or core facility setting.
Protein crystal optimisation made easy
Automated, accurate nL - µL single channel pipetting
Unifying drug discovery
Automated membrane protein screening, optimisation and scale-up
Efficient assay plate miniaturisation
Highly accurate nL - µL pipetting
mosquito® HV genomics
Enabling miniaturised molecular biology