Single cell genomics
Cost-effective plate-based workflows for single cell genomics
reproducible results from miniaturised reactions and assays
pinpoint accuracy at low volumes
increase productivity and throughput
rapid programming and high speed plate setup
generate robust, reliable data
disposable, sterilised tips ensure zero cross-contamination
develop your own protocols with ease
open system that aspirates, dispenses and mixes
reduce reagent consumption and generate more results from your budget
miniaturise costly processes and reduce dead volumes
accurate even with highly viscous liquids
unique positive displacement pipetting technology
Full-length transcriptome profiling from single cells
Full-length cDNA synthesis from single cells at a fraction of the cost of standard protocols - for deep, highly sensitive transcriptome analysis, including mRNA isoforms.
Single cell library preparation
Scaling down Nextera XT volumes by 25-fold makes NGS library preparation from a large number of samples feasible. Example applications include single cell RNA-seq and DNA-seq.
Single cell transcript counting with UMIs
A novel, miniaturised CEL-seq2 protocol enables accurate and sensitive transcriptome profiling of thousands of single cells at low cost.
A versatile liquid handling platform for single cell protocol development
Single cell genomics is an exciting and very dynamic field. New, improved chemistries and protocols are published in rapid succession, while previous methods become outdated. This poses a challenge for any single cell lab, requiring equipment with the flexibility to adapt to rapid change. mosquito® provides this flexibility, being a versatile, freely programmable, open system. mosquito empowers scientists to establish and customise their miniaturised protocols of choice, and achieve breakthroughs in single cell research output.
The technology: positive displacement pipetting
Unlike traditional liquid handlers, mosquito liquid handling robots use positive displacement pipetting technology. This superior pipetting mechanism allows transfers in the 25 nL – 5 µL range with high precision and accuracy. Importantly, it offers the ability to pipette even liquids with high viscosities, such as enzymes in 50% glycerol or genomic DNA, accurately and precisely. Furthermore, the use of disposable mosquito tips ensures gentle sample handling and zero cross-contamination.
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