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We will be at SLAS2019, visit us at booth 313

Events Category

02-06 February, 2019

See you at SLAS2019, booth 313

Venue: Walter E. Washington Convention Center
Date: 2-6 Feb 2019
Booth: 313

TTP Labtech’s portfolio of products are designed for discovery through collaboration, deep application knowledge and leading engineering. We enable scientists within drug discovery, sample management and genomics to accelerate research by improving workflow efficiency, minimising assay volumes and reducing costs. Let’s make a difference together, come see our unique range of automated liquid handling and sample management solutions at booth #313. While you’re there, register your interest in taking the dragonfly® discovery assay development challenge! 

  • arktic – biological library -20°C or -80°C automated storage
  • comPOUND – compact, secure storage and rapid automated delivery from -20°C storage
  • dragonfly discovery – acurate, automated multi-channel assay development for multifactorial assay development and validation for HTS
  • mosquito – low-cost, low-volume compound addition and dilution, assay ready plate preparation, high-speed hit picking, serial dilutions or miniaturized (nL volume) NGS library prep

Hear directly from our customers at our workshops & podium presentations:

Monday 4th February     |     Tuesday 5th February     |     Wednesday 6th February

Monday 4th February

Workshop title: From sequence to function, improving the efficiency of high-throughput genomics workflows through automation.

We have two guest speakers: David Kahler, Ph.D. PMP. Research Scientist. High Throughput Biology Laboratory, NYU School of Medicine
Talk title: Automation is key to RNAi screening at the HTB Laboratory at NYU
Guest speaker: Michael Humphrys, MSc,Laboratory Manager University of Maryland, Baltimore
Talk title: High-throughput microbiome characterization
Time: 2:00 pm – 2:45 pm
Room: 143B

Register your interest in attending this workshop here

Featured poster: Miniaturization and automation of CEL-Seq2 and SMART-Seq2 using the mosquito liquid handler 
Presenter:  Dr. Chris Waddling, TTP Labtech
Poster number: 1008-D
Time: 5:00 pm - 6:00 pm
(Scientific poster viewing time: 10:00 am – 6:00 pm) 

Customer podium presentation: The evolution of a multidimensional approach to existing and next wave technologies in delivering binding kinetics in drug discovery
Presenter: Daniel Thomas, Scientific Leader and GSK
Time: 4:00 pm - 4:30 pm

Tuesday 5th February

Workshop title: Enabling more efficient drug discovery workflows through technology innovation

Guest speaker: Daniel Thomas, Scientific Leader and GSK Associate Fellow Screening, Profiling and Mechanistic Biology, RD Platform Technology& Science, GSK Medicines Research Centre, Stevenage, UK
Talk title: Facilitating a multidimensional approach to delivering binding kinetics in drug discovery
Guest speaker: Maureen Beresini, Senior Scientist, Biochemical & Chemical Pharmacology, Genentech Inc.
Talk title: Accelerating Biochemical Assay Development through Flexible, Easy-to-Use Automation
Abstract:
Assay development is a crucial, early activity for initiating drug discovery projects. Robust and relevant assays must be put in place as rapidly as possible for identifying new chemical matter and assessing potential tool compounds as well as for establishing structure-activity relationships to drive compound progression. Assay development can be a complex, iterative, and time-consuming process. Statistical design of experiments (DoE) is one approach to streamlining the process by promoting the evaluation of multiple assay factors simultaneously, and the use of automation greatly facilitates its application. Additionally, DoE may be combined with more traditional assay development strategies to advance assays efficiently. This workshop will highlight some elements in the application of the dragonfly discovery to the execution of DoE. Additionally, it will describe the broader application of this liquid handling platform in assay development. The dragonfly® designer software fosters the use of automation across various stages of assay development because of its easy-to-use interface with flexible design features.

Time: 2:00 pm – 2:45 pm
Room: 143B

Register your interest in attending this workshop here

Wednesday 6th February

Customer podium presentation: Miniaturization of Illumina library preparation for high throughput, plate-based next generation sequencing studies
Presenters: Austin Hendricks, Jon Penterman, Stuart Levine BioMicro Center, Massachusetts Institute of Technology, Cambridge, MA
Podium Presentation Time: 2:30 pm - 3:00 pm
(Scientific podium session time: 1:30 pm - 3:30 pm)

Track Name: High-Definition Biotechnology
Session Title: High Definition Tools to Overcome Disease Complexity
Presentation Abstract:
The high cost of Illumina library production is a critical factor in the utilization of underpowered experiments. Several studies have demonstrated that increasing biological replicates, even without increasing the total amount of sequencing, significantly improves experimental power. Automated liquid handlers can address this issue through increased throughput and miniaturization of reaction volumes. However, integrating these robots in centralized facilities can be challenging due to the diverse projects, sample types, and sample qualities submitted for analysis. Here we demonstrate the miniaturization of a diverse set of Illumina library protocols on the TTP mosquito HV and their application to a broad variety of biological sample types. Methods for both RNA and DNA library production and from intact and fragmented samples have been successfully implemented and are widely used. The miniaturization of these protocols has resulted in both significant savings in library production cost, and in a notable increase in average number of replicates performed by the scientists.

Check back soon for further updates!

For more information about SLAS2019 please visit their website here