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Resources (146)

Cell-based assays

Gavine et al., AZD4547: An orally bioavailable, potent and selective inhibitor of the Fibroblast Growth Factor Receptor tyrosine kinase family. Cancer Res. 2012 Feb 27. [Epub ahead of print]

Cell-based assays, Cell-based assay screening

Titus et al., High-Throughput Multiplexed Quantitation of Protein Aggregation and Cytotoxicity in a Huntington’s Disease Model. Current Chemical Genomics, 2012, 6, 79-86

Cell-based assays, Cell-based assay screening

Sato et al., A Potent Anti-HB-EGF Monoclonal Antibody Inhibits cancer Cell Proliferation and Multiple Angiogenic Activities of HB-EGF. PLoS December 2012 ;7(12):e51964.

Cell-based assays, Cell-based assay screening

Lee et al., High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them. Methods, Eprint 5th April 2012

Cell-based assay screening

Gerlinger et al., Genome‐wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. J. Pathol 2012 Feb 24

Cell-based assays, Cell-based assay screening

Heald et al., Discovery of Novel Allosteric Mitogen-Activated Protein Kinase Kinase (MEK) 1,2 Inhibitors Possessing Bidentate Ser212 Interactions. J. Med. Chem. 2012, 55, 4594−4604

Compound management

Gaisford, W. (2012) The future of sample management: Part 1. Pharma July/August p43

Cell-based assays, Cell-based assay screening

Gaisford, W. Evolving methods in cytology: its the era of laser scanning, imaging-based technology. MLO, Dec 2011

Cell-based assays

Zhao, G et al. A Novel, Selective Inhibitor of Fibroblast Growth Factor Receptors That Shows A Potent Broad-spectrum of Anti-tumor Activity in Several Tumor Xenograft Models. MCT, Sept 2011.

Cell-based assays

Meier, T et al. Tasisulam Sodium, an Anti-tumor Agent that Inhibits Mitotic Progression and Induces Vascular Normalization. MCT, Sept 2011.

Cell-based assays

Meyvantsson et al., Image-based analysis of primary human neutrophil chemotaxis in an automated direct-viewing assay. J. Immunol. Methods. 2011 Nov 30;374 (1-2):70-7

Cell-based assays

Lu et al. 2011. Therapeutic targeting the loss of the birt-hogg-dube suppressor gene. Mol. Cancer Ther. 10(1):80-9.

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