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Resources (250)

Antibody discovery, Automated assay development

cells dispensed by dragonfly discovery show normal proliferation, health and apoptotic responses in a range of cell types

Liquid handling

Jamieson, S., et al. (2018). Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1. Sci. Signal.

Liquid handling

De Cesare, V., et al. (2018). The MALDI-TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway. Cell chemical biology

Liquid handling

Guhathakurta, P., et al. (2018). High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin-myosin structure and function. Journal of Biological Chemistry

Liquid handling

Peng, T., et al. (2018). Scope and limitations of carbohydrate hydrolysis for de novo glycan sequencing using a hydrogen peroxide/metallopeptide-based glycosidase mimetic. Carbohydrate research

Liquid handling

Lorenz, D., et al. (2018). Development and implementation of an HTS-compatible assay for the discovery of selective small-molecule ligands for pre-microRNAs. SLAS DISCOVERY: Advancing Life Sciences R&D

Liquid handling

Foote, P., et al. (2018). High‐Throughput Screening of HECT E3 Ubiquitin Ligases Using UbFluor. Current protocols in chemical biology

Cell-based assays

Koundinya, M., et al. (2018). Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers. Cell chemical biology

Cell-based assays

Feng, Y., et al. (2018). Hexon and fiber of adenovirus type 14 and 55 are major targets of neutralizing antibody but only fiber-specific antibody contributes to cross-neutralizing activity. Virology

Cell-based assays

Berenguer, J., et al. (2018). Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8. Journal of extracellular vesicles

Cell-based assays

Dobrovolsky, D., et al. (2018). Bruton's Tyrosine Kinase degradation as a therapeutic strategy for cancer. Blood

Cell-based assays

Beyleveld, G., et al. (2018). Nucleolar Relocalization of RBM14 by Influenza A Virus NS1 Protein. mSphere

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