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Resources (258)

Cell-based assays

Klanert, G., et al. (2019).. A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets. Scientific Reports

Cell-based assays

Lesch, M., et al. (2019). RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals. PLoS pathogens

Cell-based assays

Harris, I., et al. (2019).Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion. Cell metabolism

Cell-based assays

Tooze, S., et al. (2019).MDH1 and MPP7 regulate autophagy in pancreatic ductal adenocarcinoma. Cancer research

Cell-based assays

Mane, S., et al. (2019). Ascorbyl stearate stimulates cell death by oxidative stress-mediated apoptosis and autophagy in HeLa cervical cancer cell line in vitro. 3 Biotech

Cell-based assays

Van Der Steen, N., et al. (2019). Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line. Biochemical pharmacology

Cell-based assays

Lv, J., et al. (2018). Activation of A1 and A2a adenosine receptors promotes neural progenitor cell proliferation. Brain research

Cell-based assays

Miess, H., et al. (2018). The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma. Oncogene

Cell-based assays

Lavarone, C., et al. (2019). Combined MEK and BCL-2/XL inhibition is effective in high-grade serous ovarian cancer patient-derived xenograft models and BIM levels are predictive of responsiveness. Molecular Cancer Therapeutics

Antibody discovery

D'Eall, C., et al. (2019). Modulation of antibody‐dependent cellular cytotoxicity of EGFR‐specific heavy‐chain antibodies through hinge engineering. Immunology and Cell Biology

Antibody discovery

Rossotti, M., et al. (2019). Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling. Biochemical Journal

Cell-based assays

New, M., et al. (2019). Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen. Autophagy

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