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Resources (191)

Immunoassay screening, Antibody discovery

Nishiyama, K. et al. Genetic deletion of GPR52 enhances the locomotor-stimulating effect of an adenosine A2A receptor antagonist in mice: A potential role of GPR52 in the function of striatopallidal neurons (2017) Vol 1670 pp24-31

Immunoassay screening, Antibody discovery

Balmaseda, A et.al., Antibody-based assay discriminates Zika virus infection from other flaviviruses. Proc. Natl. Acad. Sci (2017) 114 (31) 8384-8389

Cell-based assay screening, Cell-based assays

Gaisford, W., Improving HCA with laser scanning imaging: Tool allows positional analysis of every cell in a single scan. GEN, 2012 Nov 15.

Liquid handling

Wildey, M, J., et al. (2017). Chapter Five - High-Throughput Screening. An Rep Med Chem. 50: 149-195

Lipidic Cubic Phase (in-meso)

Shihoya, W., et al. (2017) X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog. Nature Struc & Mol Biol. 24, 758–764.

Sitting drop crystallization

Ahmad, L., et al. (2017), Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands. FEBS Open Bio, 7: 122–132. doi:10.1002/2211-5463.12168

Hanging drop crystallization

Gautam, G., et al. (2017). Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition. Acta Cryst. D73, 672-682.

Hanging drop crystallization

Baklouti, A., et al. (2017) Toscana virus nucleoprotein oligomer organization observed in solution. Acta Cryst. D73, 650-659.

Crystal screen optimization

O’Neil, P, K., et al. (2017) The POTRA domains of Toc75 exhibit chaperone-like function to facilitate import into chloroplasts. PNAS. 114 (24) E4868-E4876

Sitting drop crystallization, Crystal screen optimization

Alcon, P., et al. (2017). Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA. Acta Cryst. F73, 409-415.

Crystal screen optimization

Debnath A., et al. (2017) CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). PLoS Negl Trop Dis 11(12): e0006104.

Cell-based assay screening, Cell-based assays

White, et al. (2017). A Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein ACS Infec Dis.

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