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A multiplexed cell-based assay for antibody screening

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The use of monoclonal antibodies against a wide range of protein targets is an expanding area for the development of therapies and biomarkers of diseases such as cancer and autoimmune disorders. Monoclonal antibodies are produced by cell lines that secrete antibodies against a specific antigen into the growth medium. High-throughput screening is central to antibody discovery programmes due to the large number of clones that need to be assessed.