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Resources (444)

Cell-based assay screening, Cell-based assays

Ming, W et al. Development and validation of a 96-well cellular assay for the discovery of ALDH1A1 inhibitors. ASSAY and Drug Development Technologies. July 2013, 11(6): 388-395

Cell-based assay screening

Horman, S et al. An HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics. J Biomol. Screen August 5, 2013

Cell-based assay screening, Cell-based assays

Horman, S et al. High-content analysis of three dimensional tumour spheroids: investigating signaling pathways using small hairpin RNA. Nature Methods. September 27, 2013

Cell-based assay screening, Cell-based assays

Horman, S et al. 3D High-content analysis of spheroids. New methodology shown to improve screening. GEN 2013, Vol. 33 (No. 16)

Lipidic Cubic Phase (in-meso)

Hollenstein, K. et al (2013) Structure of class B GPCR corticotropin-releasing factor receptor 1. Nature 499: 438–443

Lipidic Cubic Phase (in-meso)

Nakashima, R. et al (2013) Structural basis for the inhibition of bacterial multidrug exporters. Nature 500: 102–106

Plasma & serum storage, Protein storage, Biological fluids storage

Effective management of global antibody supply at Abcam

Liquid handling, Antibody discovery

Automated liquid handling of low volumes for biological assay and screen set-up

Automated on-line analysis

Fully automated sample analysis to drive efficiency and higher quality data in pharmaceutical drug discovery at Novartis

Cell-based assay screening, Cell-based assays

A rapid and robust high content analysis method for detecting protein translocation using acumen hci

Cell-based assay screening, Cell-based assays

A rapid and robust high content analysis method for detecting protein kinase phosphorylation using acumen hci

Liquid handling

Implementation of a High Throughput Screening Platform using MALDI – MS as a Readout

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