mosquito® HV genomics
Enabling miniaturised molecular biology with our multi-talented liquid handler
exceptional precision and accuracy in the 500 nL – 5 µL pipetting range, even with highly viscous samples
pre-sterilised, disposable pipettes for ensuring data integrity
rapid return on investment
affordable instrument enabling large cost savings on expensive reagents and kits
rapid plate to plate pipetting motion and tip exchange
versatile at low volume
aspirate, dispense and mix in any plate type or format
ultra-low dead volumes
maximising reagent use and preserving precious sample with dead volumes as low as 0.2 µL
User friendly and flexible; low volume pipetting at your fingertips
mosquito HV genomics provides you with highly accurate and precise low volume pipetting, picking up where traditional liquid handling falls down. mosquito can handle even highly viscous samples (e.g. genomic DNA or enzymes in 50% glycerol), operates with standard microwell plates and can be easily programmed to run a wide range of protocols, which makes mosquito an extremely versatile tool for any genomics lab.
Genomics the mosquito way; miniaturise to maximise
mosquito is changing the way genomics is done - the ability to accurately set up reactions at a fraction of the traditional volumes (often one tenth or less) leads to a step-change in productivity. NGS library preparation, magnetic bead cleanup, cDNA synthesis, whole genome amplification, PCR and qPCR all have been successfully automated and miniaturised with mosquito. Miniaturisation leads to large cost savings and allows researchers to maximise their output of results for a given budget.
Bring the benefits of positive displacement pipetting into your lab
Built for performance
Our liquid handling instruments use innovative technologies to provide real world benefits to researchers.
We produce robust, reliable and easy to use products that overcome difficult technical challenges so that you can focus on solving the scientific ones.
Positive displacement pipetting
Each of our disposable micropipettes has its own individual piston, not an air gap or system liquid, offering true positive-displacement pipetting with no risk of cross-contamination.
Our pipetting technology makes mosquito liquid handlers uniquely suited to deal with a wide range of viscosities, from organic solvents to aqueous buffers with 50% glycerol, all without any liquid classification.
Low-volume accuracy and precision
mosquito HV genomics offers low volume automated pipetting in the 500 nL to 5 µL range, to a very high level of performance, suitable even for serial dilution or quantitative PCR set-up.
- Outstanding accuracy: with an average of less than 3% error throughout the volume range
- Unrivalled precision: CVs of 3% (average across the volume range)
Linearity of volume transfer for mosquito HV
Data was obtained from 64 repeat volumes from 500nL to 5µL. % accuracy was within 2% and % c.v. was less than 3% across the volume range. Data was provided using the Artel MVS system.
Intuitive by design
Our software is as focused on usability as it is on functionality. We strive for an intuitive user experience that matches the requirements of each scientific application. Through collaboration with scientists, our software team develop and enhance the instrument UI to provide the optimal user experience and facilitate adoption into novel application areas.
Versatile workflow integration
mosquito liquid handlers have been integrated with a wide variety of other laboratory instrumentation, including robotic plate handlers, stackers and bulk liquid handlers, to achieve walk-away operation in many application areas.
The mosquito Plate Processor (MoPP) is an off-the-shelf compact bench top workcell centred around mosquito. The integration system uses the popular PreciseFlex PF400 plate handling robot and Revolution scheduler allowing a variety of third party equipment to be integrated with any of our mosquito liquid handlers.
Low-cost NGS sample preparation workflows at reduced volumes including; NGS library preparation, magnetic bead clean-up, DNA quantification and normalisation. Validated with market-leading kits such as Nextera XT and NEBNext Ultra II with up to 25-fold volume reduction compared with the manufacturer’s standard protocol.
Magnetic bead clean-up
With mosquito® HV genomics, nucleic acids can be cleaned up and size-selected with magnetic beads at high throughput, which complements miniaturised library preparation processes. A 384-well magnetic block has been specifically designed for this purpose.
Single cell genomics
mosquito® is ideal for processing single cells pre-sorted into plates. Miniaturisation of sample preparation protocols with mosquito results in a dramatically reduced cost per cell, which is essential for large-scale single cell studies. mosquito can be programmed to perform your protocols of choice, including full-length cDNA synthesis, cDNA synthesis for 3’end counting, whole genome amplification and library preparation.
PCR and qPCR
mosquito® enables automated, rapid set-up of PCR and qPCR reactions with outstanding accuracy and precision. mosquito is a useful tool for a variety of PCR applications including; gene expression profiling by qRT-PCR, DNA or library quantification, multiplex PCR and genotyping.
5 minutes/ 4 x 384 plate stamp out
15.5 in (17.3 in) x 18.5 in x 27 in
What our customers say
Interrogation of sequencing data (e.g. total reads mapped, complexity, and genes detected) indicated that the NGS libraries generated on the mosquito were of good quality. Our results demonstrate the utility, versatility, and practicality of the mosquito in a core lab.
The very best technical assistance for mosquito HV genomics from our dedicated service and support team.
Backed by our highly committed service team, our mosquito HV genomics service contracts ensure peak performance for complete peace of mind.
Dedicated in-house scientists supporting mosquito HV genomics application and assay enquiries.
Expert training gets you up and running in no time and ensures best practise, ensuring peak performance from your mosquito HV genomics.
Interested? Get in touch to start the journeyAsk an expert