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dragonfly® discovery

Significantly reduce assay development time and improve HTS efficiency

Innovative, low volume liquid handling that can significantly reduce assay development time and greatly improve assay robustness in screening.

Delivering screening efficiency through technology innovation

just walk-up and use

simple set-up and minimal maintenance

greatly improve assay robustness

accurate dispensing irrespective of liquid class

save time, sample and budget

ultra-low dead volumes

significantly reduce assay development time

complex DoE dispensing

suitable for low or high throughput assays

compatible with any SBS plate format 96 - 1,536 well

develop quality assays in a fraction of the time

independent multi-channel positive displacement technology

What bottlenecks?

The challenges associated with validating and transferring assays into HTS are well known bottlenecks in the drug discovery process. dragonfly discovery gives scientists a common platform whereby they can easily develop complex assays, validate and screen them in a reliable, robust and cost efficient manner.

Innovative technology

dragonfly discovery’s dispense technology and reliability not only simplifies the process of assay development but also significantly aids the smooth transition into HTS. With its versatility and powerful software, dragonfly discovery provides the ideal platform for hit-to-lead and lead optimisation, thus enabling the same dispense technology to be used throughout the drug discovery process.

Innovation

Non-contact dispensing from a disposable, positive displacement tip

In each of the channels (up to 10) there is a tight fitting piston that travels within a pipette barrel, when coupled to the instruments piston rod the positive displacement syringe is formed. The distance and rates of acceleration and deceleration of the piston control how and when liquid is ejected from the tip.
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We’re revolutionising liquid handling

Our liquid handling portfolio provides you with accurate and repeatable nanolitre to microliter pipetting, every time, irrespective of liquid viscosity or environmental conditions.

Built for pure performance

  • simple walk-up and use instrument
  • intuitive UI for complex assay design enables DoE
  • nothing to wash, maintain, check, calibrate prior to a run
  • easy to set up reagent reservoirs
  • smooth transition from assay development through HTS to hit-to-lead
  • automated work cell for small-scale screening
  • automation friendly for work cell integration 

dragonfly discovery

Built for pure performance

  • reliable low volume dispensing of precious reagents
  • no liquid classification or compatibility issues
  • inherently reliable technology
  • no clogging or blocking of nozzles
  • zero cross-contamination
  • reliable dispensing of challenging reagents combined with robust automation enabling efficient assay set up and screening
  • eliminates assay variation

dragonfly discovery tip technology

Built for pure performance

Non-contact dispensing from a disposable, positive displacement tip. 

In each of the channels (up to 10), there is a tight fitting piston that travels within a pipette barrel. When coupled to the instruments piston rod, the positive displacement syringe is formed. The distance and rates of acceleration and deceleration of the piston control how and when liquid is ejected from the tip.

dragonfly discovery hit-to-lead

Built for pure performance

Our software is as focused on usability as it is on functionality. We strive for an intuitive user experience that matches the requirements of each scientific application. Through collaboration with scientists, our software team develop and enhance the instrument UI to provide the optimal user experience and facilitate adoption into novel application areas.

Fully harness the power of DoE through a combination of high dynamic range non-contact dispensing of multiple liquids along with intuitive, flexible and open format software. It has been designed in close collaboration with scientists in order to ensure it meets the needs of the assay developer, as well as those scientists working within a screening environment.

 Key features include:

  • Highly visual, easy to use UI
  • Flexible sequencing of liquid additions
  • Automation of time point experiments, allowing for maximum walk-away time
  • Saving and loading of full experiment setup data, for full reproducibility
  • Intuitive definition of concentration gradients, both linear and high dynamic range n-fold

dragonfly discovery software image

Built for pure performance

dragonfly discovery can be integrated with a wide variety of robotic plate handlers.  Automation-friendly hardware, with active plate clamping and positioning, allows extensive robotic access to the plate nest, even for low profile 1,536 well plates. Integration into to large HTS screening systems or small hit-to-lead work cells is enabled via an API, providing walk-away operation in many application areas.

The dragonfly discovery AD (assay development) model includes API and manually addressable reservoirs with limited capacity (i.e. is suitable for small-scale screens only).  The dragonfly discovery HTS (High Throughput Screening) model will be available early 2019 and includes fully automated reservoir feed system for extended HTS runs.

dragonfly discovery and mirrorball intergration

Technical specifications

Pipetting range
200 nL – 4 mL
Throughput
30 seconds/ 384 well plate 5 μL fill (from 6 channels)
85 seconds/ 1,536 well plate 1 μL fill (from 6 channels)
Primary SBS plate format
96, 384 and 1,536
Weight
46 kg/ 101.4 lbs
Dimensions (W x D x H)
600 mm x 433 mm x 635.5 mm
23.6 in x 17 in x 25 in

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