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- Screening
- Applications
Applications
High-content screening is a key technology for supporting the drug discovery process from target identification through to preclinical toxicology.
TTP LabTech Screening Services has extensive experience with a wide range of assays that can be applied at key stages throughout the drug discovery process.
Our highly flexible approach to cell-based assay screening provides high-throughput, content-rich and highly multiplexed data relevant to many applications.
- Target identification
- Target validation
- Pathway profiling
- Lead identification and optimisation
- Primary screening
- Secondary screening
- Preclinical toxicology
- Assay development
These applications can be directed to different therapeutic areas such as oncology, regenerative medicine (stem cells) and cardiovascular disease by applying different high-content assays including:
- Cell cycle analysis
- Mitotic index
- Protein kinase profiling
- GPCR screening e.g. β-lactamase activation
- RNAi library profiling
- Apoptosis
- Cell differentiation and proliferation
- Cytotoxicity
- Reporter gene activation
- Stem cell phenotyping
- Angiogenesis
- C.elegans/Zebrafish phenotyping
For further information on our screening services please contact us at sales@ttplabtech.com