Applications

TTP LabTech’s RAPid 4 is biosensor system for generating high quality, real-time affinity and concentration measurements.  This is achieved using label-free acoustic detection thus avoiding costly fluorescent- or radio-labelled reagents.

The RAPid 4 can handle sample preparations ranging from complex (neat serum, urine, hybridoma supernatants or cell culture media), through to purified antigens, antibodies and receptors. This enables a wide range of molecular interactions and applications to be assessed, from small molecule profiling to bacterial and viral detection, peptides and DNA.

Use of the RAPid 4 extends from research, through drug development and into preclinical studies, and includes the following key applications:

• optimisiation of recombinant protein and antibody affinities as biopharmaceuticals
• assessment of the concentration and integrity of proteins
• isotyping of antibodies and antigens
• immunogenicity studies
• improvement of protein expression, extraction and purification processes