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Mosquito HTS
Mosquito Crystal
mosquito X1
Performance
Applications
Benefits
Specifications
 
mosquito applications
protein crystallography
The mosquito® Crystal liquid handler's accuracy is ideal for automating the set-ups used for low volume protein crystallography, including hanging drop, sitting drop and microbatch screens in almost all crystallography plate types. The positive displacement micropipettes can handle the most troublesome precipitants, including PEG and isopropanol. 
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compound handling & serial dilutions
mosquito® HTS can clone primary assay plates by adding a little as 25 nanoliters to a dry assay plate - a goal for many screeners as this avoids unnecessary dilution steps and minimises solvent concentration. Precious compounds can be saved by performing assay-ready serial dilutions in ultra-low volumes (down to 1 microliter total drop size) in 96, 384 or even 1536-well plates. Using the dilution plate as the assay plate saves a process step as well as minimising reagent usage.

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miniaturised assays
Cell-based screening in 1536-well plates is easy with mosquito's relatively wide bore, positive displacement micropipettes. Viable populations of a range of cell lines have been aliquotted into 1536-well plates, and compound screens added to enable miniature assays to be set up quickly and reliably.

genotyping
PCR is expensive. The mosquito® liquid handler reduces the reagent cost of real-time PCR and SNP genotyping by up to 90% simply by miniaturising the assay. mosquito's disposable pipette has the added benefit of eliminating cross-contamination.