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compound
handling & serial dilutions
mosquito® HTS
can clone primary assay plates by adding a little as 25 nanoliters to a
dry assay plate - a goal for many screeners as this avoids unnecessary
dilution steps and minimises solvent concentration. Precious compounds can
be saved by performing assay-ready serial dilutions in ultra-low volumes
(down to 1 microliter total drop size) in 96, 384 or even 1536-well
plates. Using the dilution plate as the assay plate saves a process step
as well as minimising reagent usage.
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miniaturised
assays
Cell-based screening in 1536-well plates is easy with mosquito's
relatively wide bore, positive displacement micropipettes. Viable
populations of a range of cell lines have been aliquotted into 1536-well
plates, and compound screens added to enable miniature assays to be
set up quickly and reliably.
genotyping
PCR is expensive. The mosquito® liquid handler reduces the reagent cost of
real-time PCR and SNP genotyping by
up to 90% simply by miniaturising the assay. mosquito's disposable
pipette has the added benefit of eliminating cross-contamination.
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